ANTI-MSL1 (CENTER)

Code: SAB1306806-400UL D2-231

Biochem/physiol Actions

The gene MSL1 (male specific lethal 1 homolog) encodes a protein associated with mammalian MOF (male-absent-on-the-first)-MSL (male-specific-lethal) c...


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€571.00 400UL
€702.33 inc. VAT

Biochem/physiol Actions

The gene MSL1 (male specific lethal 1 homolog) encodes a protein associated with mammalian MOF (male-absent-on-the-first)-MSL (male-specific-lethal) complex that is also referred to as the ‘;dosage compensation complex’; (DCC). This complex is involved in the equalization of X-chromosomal genes expression between males and females. It is found to form a complex with Nupr1 (nuclear protein 1) in the nucleus in response to DNA-damage and may be involved in DNA repair activity. MSL1 protein is found to regulate acetylation of global histone H4 via its interaction with KAT8 (lysine acetyltransferase 8).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

The gene MSL1 (male specific lethal 1 homolog) encodes a histone acetyl transferase-associated protein that spans a length of 614 amino acid residues. It does not contain any globular domains.

Physical form

Supplied in PBS with 0.09% (W/V) sodium azide

antibody formaffinity isolated antibody
antibody product typeprimary antibodies
biological sourcerabbit
clonepolyclonal
formbuffered aqueous solution
Gene Informationhuman ... MSL1(339287)
mol wt67128 Da
NCBI accession no.NP_001012241.1
Quality Level100
shipped inwet ice
species reactivityhuman
storage temp.−20°C
technique(s)western blot: 1:1000
UniProt accession no.Q68DK7
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